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Frostbite and Iloprost or Similar

Prevent | Recognise | Treat Early

Frostbite and Iloprost or Similar

Bello, J. W., Rickrode, G. A., Harlan, N. P., & Buckey, J. C. (2023). Systemic prostacyclin analogues for frostbite require careful monitoring. Journal of Burn Care & Research, 44(2), 487–488.

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Bixio, R., Adami, G., Bertoldo, E., Giollo, A., Morciano, A., Bertelle, D., Orsolini, G., Idolazzi, L., Rossini, M., & Viapiana, O. (2022). Higher body mass index is associated with a lower iloprost infusion rate tolerance and higher iloprost-related adverse events in patients with systemic sclerosis. Therapeutic Advances in Musculoskeletal Disease, 14, 1759720X221137125.

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Cauchy, E., Cheguillaume, B., & Chetaille, E. (2011). A controlled trial of a prostacyclin and rt-PA in the treatment of severe frostbite. New England Journal of Medicine, 364(2), 189–190.

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Eslami, A., & Lauver, B. (n.d.). Utilization of epoprostenol in the management of severe frostbite. Chest(Conference abstract—no DOI available)

Gauthier, J., Morris-Janzen, D., & Poole, A. (2023). Iloprost for the treatment of frostbite: A scoping review. International Journal of Circumpolar Health, 82(1), 2189552.

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Khan, S., Mooncai, T., & Sandhu, S. (n.d.). Thawing the system: Frostbite treated with epoprostenol. Chest(Conference abstract)

Law, S. T., Farber, H. W., & Simms, R. W. (2017). Use of intravenous epoprostenol as a treatment for the digital vasculopathy associated with the scleroderma spectrum of diseases. Journal of Scleroderma and Related Disorders, 2(3), 208–212.

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Poole, A., & Gauthier, J. (2016). Treatment of severe frostbite with iloprost in northern Canada. CMAJ, 188(17–18), 1255–1258.

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Poole, A., Gauthier, J., & MacLennan, M. (2021). Management of severe frostbite with iloprost, alteplase and heparin: A Yukon case series. CMAJ Open, 9(2), E585–E591.

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